Cytokines and Receptors Reagents and Kits
ANALYTICAL CONTROL SYSTEMS INC AE HEMOGLOBIN VARIANT CONTROL
NC2205038 AE HEMOGLOBIN VARIANT CONTROL
American Research Products Inc BoVine Interleukin 17A IL 17A
BoVine Interleukin 17A (IL-17A/IL-17) ELISA Kit from CUSABIO Detection Range 0 94 pg/mL-60 pg/mL Sensitivity 0 47 pg/mL Sample serum plasma tissue homogenates Method Sandwich
STEMCELL Technologies Mouse Recombinant IL-5, Size: 100 µg
Interleukin 5 (IL-5) is a member of the short-chain 4-α-helical bundle subset of hematopoietic cytokines. It binds to the specific α receptor, which in turn recruits the common β receptor that initiates signaling via JAK/STAT and MAPK pathways. IL-5 is produced by Th2 cells, eosinophils, activated mast cells, and ILC2 cells. IL-5 affects the differentiation, activation, and survival of eosinophils, thus playing an important role in allergic inflammation, asthma, and parasite immunity. Stimulation of eosinophils with IL-5 leads to their activation, upregulation of CD11b expression, and inhibition of apoptosis (Shearer).
ABclonal Technology IL8 Rabbit pAb
This gene encodes a CXC chemokine, commonly known as interleukin-8 (IL-8), a key mediator of inflammation. IL-8 is secreted by immune and epithelial cells and acts as a chemotactic factor, guiding neutrophils to infection sites. Its expression is rapidly induced by bacterial and viral products. IL-8 contributes to proinflammatory signaling and is involved in conditions such as SIRS, bronchiolitis (RSV-related), cystic fibrosis, coronary artery disease, and endothelial dysfunction. It also promotes tumor migration, invasion, angiogenesis, and metastasis. IL-8 binds to CXCR2 (IL-8RB), increasing vascular permeability, and higher IL-8 levels correlate with worse outcomes in diseases like sepsis. This gene is part of a chemokine cluster on chromosome 4q.
STEMCELL Technologies Human Recombinant IL-10, Size: 1000 µg
Interleukin 10 (IL-10) is the founding member of the IL-10 family of class II cytokines. All of the IL-10 cytokine family members have a four-helix bundle consisting of α-helical folds. Upon binding to its receptor, IL-10 activates signaling through JAK1 and STAT3. It is produced by dendritic cells, macrophages, and CD4+ T cells, as well as mast cells, NK cells, neutrophils, and B cells, under specific stimulating conditions (Saraiva & O'Garra). IL-10 can inhibit the expression of pro-inflammatory cytokines and promote healing processes, and is important for the function of regulatory T cells. IL-10 also enhances B cell proliferation, immunoglobulin secretion, and class II MHC expression, while IL-10 produced by macrophages inhibits activation of neighboring macrophages, thus allowing a level of self-regulation (Ouyang et al.).
![PBL Assay Science Human Interferon Alpha (IFN-Alpha, IFNa) Sampler Set [1e5 (100,000) units/vial]](https://assets.fishersci.com/TFS-Assets/CCG/product-images/VN00058917-11002-HU-IFN-ALPHA-SUBTYPE-SAMPLER.PNG-250.jpg)
PBL Assay Science Human Interferon Alpha (IFN-Alpha, IFNa) Sampler Set [1e5 (100,000) units/vial]
Recombinant Human Interferon Alpha proteins are manufactured by PBL Assay Science (Catalog #11002-1) for research use only (RUO) and packaged in a sampler set. This protein set contains 12 distinct human IFN-Alpha subtypes. cDNAs of IFNs are obtained from human leukocyte mRNA, expressed in E.coli and purified. These cytokines are packaged in 1e5 (100,000) units/vial.
American Research Products Inc Rat C C chemokine receptor typ
Rat C-C chemokine receptor type 2 (CCR2) ELISA kit from CUSABIO Detection Range 15 6 pg/mL-1000 pg/mL Sensitivity 3 9 pg/mL Sample serum plasma tissue homogenates Method Sandwich
American Research Products Inc Dog Interleukin 1 receptor ant
Dog Interleukin-1 receptor antagonist protein (IL1RN) ELISA kit from CUSABIO Detection Range 15 6 pg/ml-1000 pg/ml Sensitivity 3 9 pg/ml Sample serum plasma tissue homogenates Method Sandwich
American Research Products Inc Mouse chemokine C X C motif
Mouse chemokine (C-X-C motif) ligand 17 (CXCL17) ELISA kit from CUSABIO Detection Range 37 5 pg/mL-2400 pg/mL Sensitivity 9 375 pg/mL Sample serum plasma tissue homogenates Method Sandwich
American Research Products Inc BoVine interleukin 4 IL 4 ELI
BoVine interleukin 4 IL-4 ELISA Kit from CUSABIO Detection Range 12 5 pg/mL-800 pg/mL Sensitivity 3 12 pg/mL Sample serum plasma tissue homogenates Method Sandwich
Raybiotech Inc C-Series Mouse Cytokine Antibody Array 2 Kit.
Detects 32 Mouse Cytokines. Suitable for all liquid sample types. Semi-Quantitative, Sandwich-based, Membrane Antibody Array. Screen and compare protein expression levels with high specificity and sensitivity (pg/ml levels). No dedicated equipment required. Compatible with any chemiluminescent imaging system. Proteins detected: 6Ckine (CCL21), CTACK (CCL27), Eotaxin-1 (CCL11), GCSF, GM-CSF, IL-2, IL-3, IL-4, IL-5, IL-6, IL-9, IL-10, IL-12 p40/p70, IL-12 p70, IL-13, IL-17A, IFN-gamma, KC (CXCL1), Leptin, MCP-1 (CCL2), MCP-5, MIP-1 alpha (CCL3), MIP-2, MIP-3 beta (CCL19), RANTES (CCL5), SCF, TNF RI (TNFRSF1A), TARC (CCL17), TIMP-1, TNF alpha, Thrombopoietin (TPO), VEGF-A
American Research Products Inc Human chemokine C X C motif
Human chemokine (C-X-C motif) ligand 17 (CXCL17) ELISA kit from CUSABIO Detection Range 125 pg/mL-8000 pg/mL Sensitivity 31 25 pg/mL Sample serum plasma cell culture supernates urine tissue homogenates Method Sandwich
American Research Products Inc Monkey C C motif chemokine 17
Monkey C-C motif chemokine 17 (CCL17) ELISA kit from CUSABIO Detection Range 39 pg/mL-2500 pg/mL Sensitivity 9 8 pg/mL Sample serum plasma tissue homogenates Method Sandwich
Genscript Corporation IFN-γ, Mouse
Sharing 41% sequence identity with human Interferon gamma (hIFN--γ), mouse IFN gamma (mIFN--γ)is a macrophage-activating factor.The active form of IFN--γ is an antiparallel dimer that sets off IFN--γ/JAK/STAT pathway. IFN--γ signaling does diverse biological functions primarily related to host defense and immune regulation, including antiviral and antibacterial defense, apoptosis, inflammation, and innate and acquired immunity.While IFN--γ–induced inflammatory cascade summons a variety of immune-related cell types, such as macrophages, natural killer (NK) cells and cytotoxic T lymphocytes (CTLs), IFN--γ is also implicated in resistance to NK cell and CTL responses and in immune escape in avariety of cancers.
Genscript Corporation IL-1α, Human
IL-1 alpha is a non-secreted proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL-1alpha and IL-1beta binds to the same receptor and has similar if not identical biological properties. These cytokines have a broad range of activities including, stimulation of thymocyte proliferation, by inducing IL-2 release, B-cell maturation and proliferation, mitogenic FGF-like activity and the ability to stimulate the release of prostaglandin and collagenase from synovial cells. However, whereas IL-1 beta is a secreted cytokine, IL-1 alpha is predominantly a cell-associated cytokine.